Characteristic of K3 (CpG-ODN) as a Transcutaneous Vaccine Formulation Adjuvant
Transcutaneous immunization (TCI) is easy to use, minimally invasive, and has excellent efficacy in vaccines against infections.We focused on toll-like receptor here (TLR) ligands as applicable adjuvants for transcutaneous formulations and characterized immune responses.TCI was performed using poke-and-patch methods, in which puncture holes are for